7 research outputs found

    Early Prediction of Employee Turnover Using Machine Learning Algorithms

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    Employee turnover is a serious challenge for organizations and companies. Thus, the prediction of employee turnover is a vital issue in all organizations and companies. The present work proposes prediction models for predicting the turnover intentions of workers during the recruitment process. The proposed models are based on k-nearest neighbors (KNN) and random forests (RF) machine learning algorithms. The models use the dataset of employee turnover created by IBM. The used dataset includes the most essential features, which are considered during the recruitment process of the employee and may lead to turnover. These features are salary, age, distance from home, marital status, and gender. The KNN-based model exhibited better performance in terms of accuracy, precision, F-score, specificity (SP), and false-positive rate (FPR) in comparison to the RF-based model. The models predict the average probability percentage of turnover intentions of the workers. Therefore, the models can be used to aid the human resource managers to make precautionary decisions; whether the candidate employee is likely to stay or leave the job, depending on the given relevant information about the candidate employee

    Hepatoprotective potential of Malvaviscus arboreus against carbon tetrachloride-induced liver injury in rats

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    Malvaviscus arboreus Cav. is a medicinal plant belonging to family Malvaceae with both ethnomedical and culinary value; however, its phytochemical and biological profiles have been scarcely studied. Accordingly, this work was designed to explore the chemical composition and the hepatoprotective potential of M. arboreus against carbon tetrachloride (CCl4_4)-induced hepatotoxicity. The total extract of the aerial parts and its derived fractions (petroleum ether, dichloromethane, ethyl acetate, and aqueous) were orally administered to rats for six consecutive days, followed by injection of CCl4_4 (1:1 v/v, in olive oil, 1.5 ml/kg, i.p.) on the next day. Results showed that the ethyl acetate and dichloromethane fractions significantly alleviated liver injury in rats as indicated by the reduced levels of alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP), total bilirubin (TB), and malondialdehyde (MDA), along with enhancement of the total antioxidant capacities of their livers, with the maximum effects were recorded by the ethyl acetate fraction. Moreover, the protective actions of both fractions were comparable to those of silymarin (100 mg/kg), and have been also substantiated by histopathological evaluations. On the other hand, liquid chromatography-high resolution electrospray ionization mass spectrometry (LC‒HR‒ESI‒MS) metabolomic profiling of the crude extract of M. arboreus aerial parts showed the presence of a variety of phytochemicals, mostly phenolics, whereas the detailed chemical analysis of the most active fraction (i.e. ethyl acetate) resulted in the isolation and identification of six compounds for the first time in the genus, comprising four phenolic acids; β-resorcylic, caffeic, protocatechuic, and 4-hydroxyphenylacetic acids, in addition to two flavonoids; trifolin and astragalin. Such phenolic principles, together with their probable synergistic antioxidant and liver-protecting properties, seem to contribute to the observed hepatoprotective potential of M. arboreus

    The last subduction-related volcanism in the northern tip of the Arabian-Nubian Shield: A Neoproterozoic arc preceding the terminal collision of East and West Gondwana

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    The medium- to high-K calc-alkaline subduction-related Dokhan volcanic rocks of the Wadi Hamad area record two flare-up events during the history of a Neoproterozoic continental island arc, an early pulse dominated by andesite and a later pulse dominated by dacite. The trace element abundances and (La/Yb)_n ratios of the basalts, andesites and dacites all overlap, contrary to the expectations of a single fractional crystallization trend, suggesting the need for three distinct parental magmas for the three groups. The parental magmas of the basalts and andesites were generated by variable degrees of partial melting of subduction-metasomatized mantle, whereas that of the dacites requires mixing of mantle and crustal melts. The andesites and dacites both evolved mostly through fractionation of clinopyroxene and plagioclase, accompanied by apatite and Fe-Ti oxides in the more evolved dacitic rocks. Oscillatory and reverse zoning in clinopyroxene and plagioclase indicates that magma replenishment and mixing played a role in the genesis of the basalts and andesites. Depth-sensitive geochemical parameters show that the earlier andesites evolved at deeper levels in the arc crust compared with the later dacites, but not so deep as to stabilize garnet as a fractionating phase. Estimated values of the arc crust thickness indicate that the crust thickened from ∼35 km to ∼50 km from the time of basalt eruption to the time of andesite eruption, probably implying a high rate of crustal growth. The estimated arc crust thickness during the later subduction flare-up is slightly less than that of the earlier one despite ongoing magmatic addition, implying that arc crust delamination began before the production of the later dacites. The subduction-related geochemical characteristics of the Dokhan volcanic rocks suggest that the terminal collision between East and West Gondwana in the tip of the Nubian Shield occurred at ∼600 Ma

    The last subduction-related volcanism in the northern tip of the Arabian-Nubian Shield: A Neoproterozoic arc preceding the terminal collision of East and West Gondwana

    No full text
    The medium- to high-K calc-alkaline subduction-related Dokhan volcanic rocks of the Wadi Hamad area record two flare-up events during the history of a Neoproterozoic continental island arc, an early pulse dominated by andesite and a later pulse dominated by dacite. The trace element abundances and (La/Yb)_n ratios of the basalts, andesites and dacites all overlap, contrary to the expectations of a single fractional crystallization trend, suggesting the need for three distinct parental magmas for the three groups. The parental magmas of the basalts and andesites were generated by variable degrees of partial melting of subduction-metasomatized mantle, whereas that of the dacites requires mixing of mantle and crustal melts. The andesites and dacites both evolved mostly through fractionation of clinopyroxene and plagioclase, accompanied by apatite and Fe-Ti oxides in the more evolved dacitic rocks. Oscillatory and reverse zoning in clinopyroxene and plagioclase indicates that magma replenishment and mixing played a role in the genesis of the basalts and andesites. Depth-sensitive geochemical parameters show that the earlier andesites evolved at deeper levels in the arc crust compared with the later dacites, but not so deep as to stabilize garnet as a fractionating phase. Estimated values of the arc crust thickness indicate that the crust thickened from ∼35 km to ∼50 km from the time of basalt eruption to the time of andesite eruption, probably implying a high rate of crustal growth. The estimated arc crust thickness during the later subduction flare-up is slightly less than that of the earlier one despite ongoing magmatic addition, implying that arc crust delamination began before the production of the later dacites. The subduction-related geochemical characteristics of the Dokhan volcanic rocks suggest that the terminal collision between East and West Gondwana in the tip of the Nubian Shield occurred at ∼600 Ma

    Global economic burden of unmet surgical need for appendicitis

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    Background There is a substantial gap in provision of adequate surgical care in many low- and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and92 492 million using approach 1 and 73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and95 004 million using approach 1 and 75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially
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